Febuxostat
Also sold as: Uloric, Adenuric, Febustat
Prescription neededGout
Comes as:Tablet
Usual adult dose
Usual adult dose: 40 to 80 mg once a day. The doctor may give colchicine or a painkiller for the first months to prevent gout attacks.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- more gout attacks at first
- nausea
- diarrhoea
- headache
- rash
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- chest pain
- weakness of one side of the body or trouble speaking
- yellow eyes or skin
- severe skin rash
Do not take it, or take care, if
- Taking azathioprine (dangerous combination)
- Heart disease or previous stroke (use with caution; the doctor may prefer allopurinol)
- Serious liver disease
Interactions
Medicines that can react with this one.
Serious1 medicineDo not take these together unless your doctor says so.
- Azathioprine
Febuxostat greatly raises azathioprine levels and can cause severe bone marrow damage; do not use together.