Isosorbide dinitrate
Also sold as: Isordil, Sorbitrate
Prescription neededChest pain and heart rhythm
Comes as:Tablet
Usual adult dose
To prevent angina: 10 to 20 mg two or three times a day (up to 40 mg), leaving a gap of 8 hours or more without a dose each day so it keeps working. Sublingual 5 mg tablets can be used for chest pain as directed by your doctor.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- headache
- flushing
- dizziness
- fast heartbeat
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- fainting
- very low blood pressure
Do not take it, or take care, if
- Taking sildenafil or similar medicines
- Very low blood pressure
- Severe anaemia
- Severe narrowing of the aortic heart valve
Interactions
Medicines that can react with this one.
Serious1 medicineDo not take these together unless your doctor says so.
- Sildenafil
Nitrates with sildenafil can cause a dangerous fall in blood pressure; never combine.