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Calcium channel blockers

Diltiazem

Also sold as: Cardizem, Herbesser

Prescription neededCalcium channel blockers
Comes as:TabletCapsule

Usual adult dose

Angina: standard tablets 60 mg three times a day. Long-acting forms: 90 to 180 mg twice a day or 180 to 360 mg once a day, depending on the product and as set by your doctor.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • swollen ankles
  • headache
  • dizziness
  • flushing
  • constipation

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • very slow heartbeat
  • fainting
  • worsening heart failure
  • severe skin rash

Do not take it, or take care, if

  • Very slow heartbeat or heart block
  • Heart failure with weak heart muscle
  • Low blood pressure
  • Taking a beta blocker (only if your doctor says so)

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Simvastatin

    Diltiazem raises simvastatin levels and the risk of muscle damage; keep simvastatin at 10 mg or less.

Moderate5 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Atenolol

    Together they can slow the heart too much and lower blood pressure.

  • Bisoprolol

    Together they can slow the heart too much and lower blood pressure.

  • Digoxin

    Diltiazem raises digoxin levels and slows the heart further.

  • Metoprolol

    Together they can slow the heart too much and lower blood pressure.

  • Timolol

    Together they can slow the heart and lower blood pressure.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Verapamil
  • Amlodipine
  • Nifedipine
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.