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Penicillins

Cloxacillin

Also sold as: Orbenin

Prescription neededPenicillins
Comes as:CapsuleInjection

Usual adult dose

Usual adult dose: 500 mg every 6 hours, taken 1 hour before food, usually for 5 to 7 days for skin infections. Finish the full course. Injection dose is set by your doctor.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • diarrhoea
  • nausea
  • mild skin rash

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction
  • yellow eyes or skin
  • severe or bloody diarrhoea

Do not take it, or take care, if

  • Allergy to penicillin or any penicillin-type antibiotic
  • Liver problems (use with caution)
  • Severe kidney disease (dose may need to be lowered)

Interactions

Medicines that can react with this one.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Warfarin

    Can lower the effect of warfarin; INR should be checked during the course.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Cefalexin
  • Clindamycin
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.