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Diabetes tablets

Sitagliptin

Also sold as: Januvia

Prescription neededDiabetes tablets
Comes as:Tablet

Usual adult dose

Usual adult dose: 100 mg once a day, with or without food. Lower doses (50 or 25 mg) are used in kidney disease.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • headache
  • runny or blocked nose
  • sore throat
  • joint pain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe stomach pain spreading to the back (pancreatitis)
  • severe allergic reaction or blistering skin

Do not take it, or take care, if

  • Type 1 diabetes or diabetic ketoacidosis
  • History of pancreatitis (use with caution)
  • Kidney disease (dose must be reduced)

Interactions

Medicines that can react with this one.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Glimepiride

    The combination increases the risk of low blood sugar; the sulfonylurea dose may need to be lowered.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

Minor1 medicineUsually not a problem, but tell your doctor.
  • Digoxin

    Sitagliptin can slightly raise digoxin levels; monitoring may be needed.

Vildagliptin
  • Metformin
  • Empagliflozin
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.