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Cephalosporins

Ceftriaxone

Also sold as: Rocephin

Prescription neededCephalosporins
Comes as:Injection

Usual adult dose

Dose is set by your doctor. Given by injection into a muscle or vein, usually 1 to 2 g once a day. It must not be given in the same drip line as calcium-containing fluids.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • pain at the injection site
  • diarrhoea
  • mild skin rash

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction (swelling of face or throat
  • difficulty breathing)
  • severe or bloody diarrhoea
  • yellow eyes or skin

Do not take it, or take care, if

  • Allergy to cephalosporins
  • Severe allergic reaction to penicillin in the past (use with caution)
  • Newborn babies with jaundice, or newborns receiving calcium drips

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Ringer's lactate

    Must not be mixed or given in the same line with calcium-containing fluids; dangerous deposits can form, especially in newborns.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

severe skin rash with blisters
Minor1 medicineUsually not a problem, but tell your doctor.
  • Warfarin

    May raise the effect of warfarin; INR may need checking.

Cefotaxime
  • Cefixime
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.