Propylthiouracil
Prescription neededThyroid medicines
Comes as:Tablet
Usual adult dose
Dose is set by your doctor; a usual adult starting dose is 50 to 150 mg three times a day, then lowered. It is mainly used in the first 3 months of pregnancy or when other thyroid medicines cannot be used.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- nausea
- rash
- itching
- joint pain
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- sore throat
- fever or mouth ulcers (low white cells)
- yellow eyes or skin
- dark urine
- severe tiredness (liver damage)
Do not take it, or take care, if
- Liver disease
- Previous serious blood or liver reaction to this medicine
- After the first 3 months of pregnancy the doctor usually switches to another medicine
Interactions
Medicines that can react with this one.
Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
- Warfarin
Propylthiouracil can change the effect of warfarin; INR should be checked.