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Malaria medicines

Artemether + Lumefantrine

Also sold as: Coartem

Prescription neededMalaria medicines
Comes as:TabletDissolving tablet

Usual adult dose

Adults and children over 35 kg: 4 tablets (20/120 mg) per dose, 6 doses over 3 days (at 0, 8, 24, 36, 48 and 60 hours). Take with fatty food or milk. Children: dose by weight — ask your doctor or pharmacist.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • headache
  • dizziness
  • loss of appetite
  • tiredness
  • muscle and joint pain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • fainting or irregular heartbeat
  • severe allergic reaction
  • seizures

Do not take it, or take care, if

  • Severe malaria (needs injection treatment in hospital)
  • Allergy to artemether or lumefantrine
  • Heart rhythm problems (long QT)
  • First 3 months of pregnancy (only if a doctor decides)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Amiodarone

    Both prolong the QT interval and can cause dangerous heart rhythms.

  • Rifampicin

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

Rifampicin strongly lowers artemether and lumefantrine levels; treatment may fail.

Dihydroartemisinin + Piperaquine
  • Artesunate
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.