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Antipsychotics

Chlorpromazine

Also sold as: Largactil

Prescription neededAntipsychotics
Comes as:TabletSyrupInjection

Usual adult dose

Dose is set by your doctor. For mental illness, common doses are 25 mg to 100 mg two or three times a day. Injections are given only by a health worker.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • dizziness on standing up
  • dry mouth
  • constipation
  • stiffness or shaking
  • skin burns easily in the sun

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • high fever with stiff muscles and confusion
  • yellow eyes or skin

Do not take it, or take care, if

  • Coma or severe drowsiness from alcohol or other medicines
  • Parkinson's disease
  • Older people with dementia
  • Liver disease (use with caution)
  • Epilepsy, glaucoma or enlarged prostate (use with caution)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Amiodarone

    Both prolong the QT interval and can cause dangerous heart rhythms.

  • Levodopa + Carbidopa

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

fast or irregular heartbeat
  • seizures
  • sore throat with fever
  • Chlorpromazine blocks the effect of levodopa and can worsen Parkinson symptoms.

    Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
    • Tramadol

      The combination increases the risk of seizures and drowsiness.

    • Trihexyphenidyl

      Together they increase anticholinergic side effects such as dry mouth and confusion.

    Haloperidol
  • Olanzapine
  • Risperidone
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.