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Worm and parasite medicines

Metronidazole

Also sold as: Flagyl

Prescription neededWorm and parasite medicines
Comes as:TabletSuspensionDrip (infusion)GelVaginal pessary

Usual adult dose

Usual adult dose: 400 to 500 mg two or three times a day for 5 to 7 days. Amoebic dysentery: 800 mg three times a day for 5 days. Giardia: 2 g once a day for 3 days. No alcohol during treatment and for 48 hours after. Children: dose by weight — ask your doctor.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • nausea
  • metallic taste
  • loss of appetite
  • dark urine

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction
  • numbness or tingling in hands and feet
  • seizures
  • severe skin rash

Do not take it, or take care, if

  • Drinking alcohol during treatment and for 48 hours after
  • First 3 months of pregnancy (ask your doctor)
  • Severe liver disease
  • Nerve or brain disorders (use with caution)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Mebendazole

    The combination has been linked to severe skin reactions; avoid.

  • Warfarin

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Tinidazole
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.

Metronidazole strongly raises the effect of warfarin and the risk of bleeding; INR must be checked.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Lithium carbonate

    Metronidazole can raise lithium levels to toxic levels.

  • Phenytoin

    Metronidazole can raise phenytoin levels.