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Mood stabilisers

Lithium carbonate

Also sold as: Priadel, Lithosun

Prescription neededMood stabilisers
Comes as:Tablet

Usual adult dose

Dose is set by your doctor and adjusted with regular blood tests (lithium level). Drink enough water every day, keep your salt intake steady, and do not stop it suddenly.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • thirst
  • passing a lot of urine
  • mild hand shaking
  • nausea
  • weight gain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe shaking
  • vomiting and diarrhoea
  • unsteady walking
  • confusion or slurred speech (signs of lithium poisoning)
  • fainting or irregular heartbeat

Do not take it, or take care, if

  • Kidney disease
  • Heart disease
  • Underactive thyroid (needs regular checks)
  • Dehydration or a low-salt diet
  • Pregnancy (especially the first 3 months) and breastfeeding

Interactions

Medicines that can react with this one.

Serious9 medicinesDo not take these together unless your doctor says so.
  • Captopril

    ACE inhibitors raise lithium levels and the risk of toxicity.

  • Chlortalidone

    Thiazide-like diuretics raise lithium levels and the risk of toxicity.

  • Enalapril

    ACE inhibitors raise lithium levels; lithium must be checked closely.

  • Hydrochlorothiazide

    Thiazide diuretics raise lithium levels and can cause lithium poisoning.

  • Ibuprofen

    NSAIDs such as ibuprofen raise lithium levels and can cause lithium poisoning.

  • Indapamide

    Indapamide raises lithium levels and the risk of toxicity.

Show 3 more
  • Lisinopril

    ACE inhibitors raise lithium levels and the risk of toxicity.

  • Perindopril

    ACE inhibitors raise lithium levels and the risk of toxicity.

  • Ramipril

    ACE inhibitors raise lithium levels and the risk of toxicity.

Moderate17 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Candesartan

    ARBs can raise lithium levels; levels should be checked.

  • Celecoxib

    Can raise lithium levels in the blood; levels may need checking.

  • Diclofenac

    Can raise lithium levels in the blood; levels may need checking.

  • Furosemide

    Furosemide can raise lithium levels.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Sodium valproate
  • Carbamazepine
  • Lamotrigine
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.

  • Haloperidol

    Rarely the combination causes confusion and nerve toxicity; watch closely.

  • Indometacin

    Can raise lithium levels in the blood; levels may need checking.

  • Show 11 more
    • Irbesartan

      ARBs can raise lithium levels; levels should be checked.

    • Ketorolac

      Can raise lithium levels in the blood.

    • Mefenamic acid

      Can raise lithium levels in the blood; levels may need checking.

    • Meloxicam

      Can raise lithium levels in the blood; levels may need checking.

    • Methyldopa

      Methyldopa can increase lithium side effects.

    • Metronidazole

      Metronidazole can raise lithium levels to toxic levels.

    • Naproxen

      Can raise lithium levels in the blood; levels may need checking.

    • Piroxicam

      Can raise lithium levels in the blood; levels may need checking.

    • Povidone-iodine

      Long use of iodine with lithium increases the risk of an underactive thyroid.

    • Tinidazole

      Tinidazole can raise lithium levels.

    • Valsartan

      ARBs can raise lithium levels; levels should be checked.