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Strong painkillers (opioids)

Pethidine

Also sold as: Demerol

Prescription neededStrong painkillers (opioids)
Comes as:Injection

Usual adult dose

Dose is set by your doctor. Given by injection in hospital for short-term severe pain, for example during labour. Not for long-term use.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • nausea
  • vomiting
  • dizziness
  • drowsiness
  • sweating

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow breathing
  • seizures
  • low blood pressure
  • confusion or agitation

Do not take it, or take care, if

  • Severe breathing problems
  • Severe kidney disease
  • Epilepsy
  • Head injury
  • Taking antidepressants (use with caution)

Interactions

Medicines that can react with this one.

Serious3 medicinesDo not take these together unless your doctor says so.
  • Diazepam

    Together they can cause deep sleepiness and dangerously slow breathing.

  • Fluoxetine

    Risk of serotonin syndrome.

  • Sertraline

    Risk of serotonin syndrome.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Morphine
  • Tramadol
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.