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Strong painkillers (opioids)

Morphine

Also sold as: MST Continus

Prescription neededStrong painkillers (opioids)
Comes as:TabletOral solutionInjection

Usual adult dose

Dose is set by your doctor and adjusted to the pain. Usually given for severe pain in hospital, or as tablets or liquid for cancer pain under a doctor. Never change the dose yourself.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • constipation
  • nausea
  • vomiting
  • drowsiness
  • itching

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or shallow breathing
  • very small pupils with extreme sleepiness
  • low blood pressure
  • confusion

Do not take it, or take care, if

  • Severe breathing problems or an acute asthma attack
  • Head injury
  • Bowel blockage
  • Taking other sedatives such as diazepam (use with caution)
  • History of drug addiction (only under close supervision)

Interactions

Medicines that can react with this one.

Serious9 medicinesDo not take these together unless your doctor says so.
  • Alprazolam

    Together they can cause deep sedation, slowed breathing and death.

  • Clonazepam

    Together they can cause deep sedation, slowed breathing and death.

  • Diazepam

    Together they can cause deep sleepiness and dangerously slow breathing.

  • Gabapentin

    Raises the risk of drowsiness and slow breathing.

  • Lorazepam

    Together they can cause deep sedation, slowed breathing and death.

  • Midazolam

    Together they can cause deep sedation and dangerously slow breathing.

Show 3 more
  • Naloxone

    Naloxone reverses the effects of morphine, including pain relief.

  • Pregabalin

    Together they increase sedation and the risk of slowed breathing.

  • Promethazine

    Combined use can cause deep sedation and dangerously slowed breathing.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Diphenhydramine

    Combined use increases drowsiness and the risk of slowed breathing.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Pethidine
  • Tramadol
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.