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Anxiety and sleep (sedatives)

Lorazepam

Also sold as: Ativan

Prescription neededAnxiety and sleep (sedatives)
Comes as:TabletInjection

Usual adult dose

Usual adult dose for anxiety: 1 mg to 4 mg a day in divided doses, for a short time only. The injection is used in hospital, for example to stop a long seizure. Do not stop suddenly after long use.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • tiredness
  • unsteady walking
  • poor memory

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or shallow breathing
  • severe confusion
  • falls in older people
  • dependence and seizures if stopped suddenly

Do not take it, or take care, if

  • Severe breathing problems or sleep apnoea
  • Severe liver disease
  • Myasthenia gravis
  • Use of alcohol or opioid medicines
  • Pregnancy and breastfeeding
  • Older people (use with caution — risk of falls)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Morphine

    Together they can cause deep sedation, slowed breathing and death.

  • Tramadol

    Together they can cause deep sedation and slowed breathing.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Pregabalin

    Both cause drowsiness; together they increase sedation and falls.

  • Sodium valproate

    Valproate raises lorazepam levels; a lower lorazepam dose may be needed.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Diazepam
  • Alprazolam
  • Clonazepam
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.