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Anxiety and sleep (sedatives)

Diazepam

Also sold as: Valium, Calmpose

Prescription neededAnxiety and sleep (sedatives)
Comes as:TabletInjection

Usual adult dose

Usual adult dose for anxiety: 2 mg to 5 mg two or three times a day, for a short time only (no more than 2 to 4 weeks). It can cause dependence — do not stop suddenly after long use. Injections are given only in a health facility.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • tiredness
  • unsteady walking
  • poor memory

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or shallow breathing
  • severe confusion
  • falls in older people
  • dependence and seizures if stopped suddenly

Do not take it, or take care, if

  • Severe breathing problems or sleep apnoea
  • Severe liver disease
  • Myasthenia gravis
  • Use of alcohol or opioid medicines
  • Pregnancy and breastfeeding
  • Older people (use with caution — risk of falls)
  • History of drug or alcohol dependence

Interactions

Medicines that can react with this one.

Serious5 medicinesDo not take these together unless your doctor says so.
  • Codeine

    Together they can cause deep sleepiness and dangerously slow breathing.

  • Morphine

    Together they can cause deep sedation, slowed breathing and death.

  • Pethidine

    Together they can cause deep sleepiness and dangerously slow breathing.

  • Phenobarbital

    Together they can cause deep sedation and slowed breathing.

  • Tramadol

    Together they can cause deep sedation and slowed breathing.

Moderate14 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Amitriptyline

    Both cause drowsiness; together they increase sedation and falls.

  • Baclofen

    Together they increase drowsiness and can slow breathing.

  • Chlorphenamine

    Together they cause more drowsiness and slowed reactions.

  • Cinnarizine

    Together they increase drowsiness.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Lorazepam
  • Clonazepam
  • Alprazolam
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.

  • Dimenhydrinate

    Together they cause more drowsiness and slowed reactions.

  • Diphenhydramine

    Together they cause more drowsiness and slowed reactions.

  • Show 8 more
    • Flunarizine

      Together they increase drowsiness.

    • Hydroxyzine

      Together they cause more drowsiness and slowed reactions.

    • Ketotifen

      Ketotifen tablets add to the drowsiness caused by sedatives.

    • Methocarbamol

      Together they increase drowsiness and dizziness.

    • Mirtazapine

      Both cause drowsiness; together they slow thinking and reactions more.

    • Olanzapine

      Together they increase drowsiness and can lower blood pressure.

    • Pregabalin

      Both cause drowsiness; together they increase sedation and breathing problems.

    • Promethazine

      Together they cause more drowsiness and slowed breathing.