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Anxiety and sleep (sedatives)

Midazolam

Also sold as: Dormicum

Prescription neededAnxiety and sleep (sedatives)
Comes as:Injection

Usual adult dose

Used only in a hospital or clinic, for sedation before procedures or to stop a long seizure. The dose is set by the doctor and given by a trained health worker.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • not remembering the procedure
  • hiccups
  • nausea

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or stopped breathing
  • very low blood pressure

Do not take it, or take care, if

  • Severe breathing problems or sleep apnoea without breathing support
  • Myasthenia gravis
  • Shock or very low blood pressure
  • Pregnancy (ask your doctor)

Interactions

Medicines that can react with this one.

Serious4 medicinesDo not take these together unless your doctor says so.
  • Clarithromycin

    Clarithromycin greatly raises midazolam levels and prolongs sedation.

  • Erythromycin

    Erythromycin greatly raises midazolam levels and prolongs sedation.

  • Itraconazole

    Itraconazole greatly raises midazolam levels and prolongs sedation.

  • Morphine

    Together they can cause deep sedation and stopped breathing.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Diazepam
  • Lorazepam
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.