Daclatasvir
Also sold as: Daklinza, Natdac
Prescription neededAntivirals
Comes as:Tablet
Usual adult dose
Dose is set by your doctor. Usual adult dose: 60 mg once a day together with sofosbuvir, usually for 12 weeks. The dose is changed if you take certain other medicines.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- headache
- tiredness
- nausea
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- very slow heartbeat (with sofosbuvir and amiodarone)
- hepatitis B flare in people who also carry hepatitis B
Do not take it, or take care, if
- Taking rifampicin, carbamazepine or phenytoin
- Taking amiodarone
- Pregnancy (ask your doctor)
Interactions
Medicines that can react with this one.
Serious4 medicinesDo not take these together unless your doctor says so.
- Amiodarone
With sofosbuvir-based treatment, amiodarone can cause dangerously slow heartbeat.
- Carbamazepine
Carbamazepine strongly lowers daclatasvir levels; do not combine.
- Phenytoin
Phenytoin strongly lowers daclatasvir levels; do not combine.
- Rifampicin
Rifampicin strongly lowers daclatasvir levels; do not combine.