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Beta blockers

Propranolol

Also sold as: Inderal

Prescription neededBeta blockers
Comes as:Tablet

Usual adult dose

High blood pressure: 40 to 80 mg twice a day. Migraine prevention or tremor: 40 mg two or three times a day, usual total 80 to 160 mg a day. Do not stop suddenly.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • tiredness
  • cold hands and feet
  • slow heartbeat
  • bad dreams
  • trouble sleeping

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • very slow heartbeat
  • fainting
  • wheezing or breathlessness
  • worsening heart failure (swollen legs)

Do not take it, or take care, if

  • Asthma or chronic lung disease with wheezing
  • Very slow heartbeat or heart block
  • Uncontrolled heart failure
  • Diabetes (can hide signs of low blood sugar; use with caution)
  • Do not stop suddenly

Interactions

Medicines that can react with this one.

Serious5 medicinesDo not take these together unless your doctor says so.
  • Adrenaline

    Propranolol can block adrenaline and cause a dangerous rise in blood pressure with slow heartbeat.

  • Budesonide + Formoterol

    Non-selective beta blockers block formoterol and can trigger severe bronchospasm.

  • Clonidine

    If clonidine is stopped while taking propranolol, blood pressure can rise dangerously.

  • Fluticasone + Salmeterol

    Non-selective beta blockers block salmeterol and can trigger severe bronchospasm.

  • Verapamil

    Together they can cause very slow heartbeat, heart block and heart failure.

Moderate9 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Biphasic isophane insulin 30/70

    Beta blockers can hide the warning signs of low blood sugar.

  • Glibenclamide

    Propranolol can hide the warning signs of low blood sugar.

  • Glimepiride

    Beta blockers can hide the warning signs of low blood sugar.

  • Insulin aspart

    Beta blockers can hide the warning signs of low blood sugar.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Atenolol
  • Metoprolol
  • Bisoprolol
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.

  • Insulin glargine

    Beta blockers can hide the warning signs of low blood sugar.

  • Insulin isophane (NPH)

    Beta blockers can hide the warning signs of low blood sugar.

  • Show 3 more
    • Insulin soluble (regular)

      Beta blockers can hide the warning signs of low blood sugar.

    • Lidocaine

      Propranolol can raise lidocaine levels and the risk of toxicity.

    • Salbutamol

      Propranolol blocks the effect of salbutamol and can trigger wheezing.