Clonidine
Also sold as: Catapres
Usual adult dose
Usual adult dose: 50 to 100 micrograms three times a day, increased slowly as set by your doctor (maximum 1.2 mg a day). Never stop suddenly, because blood pressure can rise dangerously.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- dry mouth
- sleepiness
- dizziness
- constipation
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- very slow heartbeat
- fainting
- dangerous rise in blood pressure after stopping suddenly
Do not take it, or take care, if
- Very slow heartbeat or heart block
- Depression (use with caution)
- People who may often miss doses
- Do not stop suddenly
Interactions
Medicines that can react with this one.
Serious1 medicineDo not take these together unless your doctor says so.
- Propranolol
Stopping clonidine while on a beta blocker can cause a severe rise in blood pressure; the beta blocker is stopped first.
Moderate4 medicinesTake together only with care. Ask your doctor or pharmacist.
- Amitriptyline
Tricyclic antidepressants reduce the blood pressure effect of clonidine.
- Atenolol
If clonidine is stopped while taking a beta blocker, blood pressure can rise sharply.
- Imipramine
Imipramine can reduce the blood-pressure-lowering effect of clonidine.
- Tizanidine
Together they can cause low blood pressure and slow heartbeat.