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Asthma and breathing

Fluticasone + Salmeterol

Also sold as: Seretide, Advair

Prescription neededAsthma and breathing
Comes as:Inhaler

Usual adult dose

Dose is set by your doctor. Usual adult dose: 1 inhalation twice a day (dry-powder inhaler) or 2 puffs twice a day (spray inhaler). Use every day; it is not for quick relief of an attack. Rinse your mouth after use.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • hoarse voice
  • mouth thrush
  • headache
  • shaking
  • muscle cramps

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • chest pain or irregular heartbeat
  • worsening wheeze right after use
  • pneumonia in COPD patients (fever

Do not take it, or take care, if

  • Not for the relief of a sudden attack
  • Heart disease or irregular heartbeat (use with caution)
  • Untreated tuberculosis of the lungs (use with caution)
  • Do not stop suddenly without your doctor

Interactions

Medicines that can react with this one.

Serious3 medicinesDo not take these together unless your doctor says so.
  • Clarithromycin

    Clarithromycin raises salmeterol levels and can cause heart rhythm problems; avoid the combination.

  • Ketoconazole

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

cough with phlegm)
  • severe allergic reaction
  • Ketoconazole greatly raises salmeterol and fluticasone levels, risking heart rhythm problems and steroid effects.

  • Propranolol

    Non-selective beta blockers block salmeterol and can trigger severe bronchospasm.

  • Budesonide + Formoterol
  • Beclometasone
  • Budesonide
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.