Fluconazole
Also sold as: Diflucan, Forcan
Usual adult dose
Usual adult dose for vaginal thrush: one 150 mg capsule as a single dose. Other fungal infections: 50 to 400 mg once a day, as prescribed by your doctor.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- nausea
- stomach pain
- headache
- diarrhoea
- rash
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- severe allergic reaction (swelling of face or throat)
- yellow eyes or skin
- severe skin rash with peeling
- fast or irregular heartbeat
Do not take it, or take care, if
- Pregnancy (avoid, especially high or repeated doses)
- Severe liver disease
- Heart rhythm problems (use with caution)
- Known allergy to azole antifungals
Interactions
Medicines that can react with this one.
Serious6 medicinesDo not take these together unless your doctor says so.
- Amiodarone
Both can prolong the QT interval and cause dangerous heart rhythms.
- Glibenclamide
Fluconazole raises glibenclamide levels and can cause dangerous low blood sugar.
- Gliclazide
Fluconazole raises gliclazide levels and can cause severe low blood sugar.
- Glimepiride
Fluconazole raises glimepiride levels and can cause severe low blood sugar.
- Simvastatin
Fluconazole raises simvastatin levels and the risk of muscle damage.
- Warfarin
Fluconazole strongly raises the effect of warfarin and the risk of bleeding; INR must be checked.